{"componentChunkName":"component---common-build-question-tags-template-js","path":"/question-tag/cbd/64","result":{"data":{"allQuestion":{"edges":[{"node":{"id":"Question_10761-markdown","title":"How long can a high last from edibles? What is a good way to bring patient down some?","slug":"how-long-can-a-high-last-from-edibles-what-is-a-good-way-to-bring-patient-down-some","content":"\"My adult son has been taking home-baked edibles for about a month now for pain relief. Things were working out fine until he took too much (two brownies and 5 cookies). It's been three days now and he's still high from this dose. He went through a panic attack that lasted a night, followed by normal \"high\" talking and activities for three days and ongoing. He also takes percocet (3 doses of 10 mg/day), along with heart meds (digoxin, lisinopril, Coreg and coumadin). \nI've never heard of anyone being high for three-plus days on one dose of cannabis. He isn't sleeping much and we're getting tired of all the nursing this is requiring from us. \nWe've recently tried giving him CBD tincture, lemon juice, food and fluids. We've ordered CannaRelief and will try it when it gets here. Nothing seems to be bringing him back down. \nHow long can this last? What else can we do to get him back to reality? \"\n_____________________\nI am not a doctor but have seen various responses to cannabis.Many have used CBD to help \"offset\" the effects of THC. Staying calm, drinking water and reducing the dose will help avoid any \"overdose\" type effects. Most edibles will last up to 4 hours but some people may be more sensitive to THC effects and have complained of effects lasting over 6 hours.\n\nredheadguy8505\n_____________________\nUnfortunately with extremely high doses of cannabis edibles, it can take 24+ hours for the body to process the THC out. Fortunately, cannabis is non-toxic and will have no lasting damage- but the experience can be incredibly uncomfortable. Other than taking a CBD-only product, he can try chewing on some black peppercorns (yes, that's a thing!), drinking some cranberry juice (which can aid in the process of detoxing), the only treatment is getting a lot of rest. It's because of experiences like these that we recommend patients start with a 5MG dose to see how it effects them. It can be difficult to gauge the amount of THC in homemade edibles, so starting with a small piece and waiting two hours before consuming more is always good practice. Hoping he's feeling a lot better now :)\n\nchristiestrong","image":null}},{"node":{"id":"Question_10760-markdown","title":"Can CBD drops help my migraines and chronic pain?","slug":"can-cbd-drops-help-my-migraines-and-chronic-pain","content":"\n_____________________\nThe short answer is yes, and this is one of the most commonly recommended purposes for CBD tinctures! CBD acts on the same endocannabinoid receptors, found throughout the body, as THC; but it seems particularly effective in treating pain and does not have the psychoactive effects of THC. It does have sedative properties but typically patients find that they are highly functional with high CBD / low THC formulations. \n\nMany patients carry an oral tincture and apply the drops or spray under their tongue for approximately ten seconds when symptoms indicating onset of migraine occur; this may blunt the severity of migraine and in the best cases reverse them. The tincture may also be added to food or beverages and ingested for longer acting treatment of pain.\n\ndredmunds\n_____________________\nYes, CBD drops can help you with migraine problem and you can also get relief from chronic pain. CBD is the major non-psychoactive component of Cannabis sativa which has antipsychotic effects and also reduces anxiety. \n\nadmin4356","image":null}},{"node":{"id":"Question_10758-markdown","title":"Part 2 (I bought Charlotte's Web, not sure I got it right. )","slug":"part-2-i-bought-charlottes-web-not-sure-i-got-it-right","content":"\"Thank you, doctor! Sorry, but I'm confused again, as it says 28 mg of hemp oil under the 'supplement facts' table. Before I take too much can you please tell me if this is the same as JJ after all? I'm wondering roughly how many drops this a day? \nAnd, this legal in all states to buy? I read a website that says it's not considered an illegal drug. That contradicts why everyone is angry at the govt for not letting people get this miracle med. If so, does that mean I can fly with it? \nAnd, another website also said you wont flunk a drug test with any of the CBD products. That sounds wrong to me. \nI'm sorry to keep asking Q's but don't know where else to go for answers. \nGreat news about your patients! How wonderful! \n\nFor one, I went to two dispensaries and no one seemed to know much about CBD oil. I told them I needed a super high oil 28:1 ratio and got blank stares and offered edibles instead. I was looking for a Jayden's Juice equivalent. I ended up with Charlotte's Web hemp extract in MCT 500 mg in 1 oz. dropper bottle. I was confident this was close to the JJ but now I'm not sure on the mg part. And it was only $60 which seemed low for CBD oil. Did I get the right kind? Thanks.\"\n_____________________\nYou are fine. Charlotte's Web is a high quality oil where the CBD is extracted from hemp, yielding a dosage of 16.67mg CBD per ml. Hemp is cannabis sativa with less than 0.3% THC. It has cannabinoids and terpenes and has very low amounts of THC (I am guessing probably no more than 0.6 - 0.8mg/ml). Jayden's Juice has almost twice as much CBD per ml - 28mg/ml of CBD and 1mg/ml THC. In order to dispense 28mg of CBD, you will have to take 1.68ml of Charlottes Web. I have several patients who use Charlotte's Web to treat seizures and one patient with lymphoma whose tumors are shrinking.************* I calculated the amount of CBD based on the information you provided - 500mg in 1 oz. One oz = 30 mL. 500/30 = 16.67mg/mL. The 28mg may refer to the total amount of hemp extract, which contains other things.  You may want to contact CW Botanicals to find out if the 28mg is referring to the total amount of extract or the total amount of cannabinoids.\n\ndrfrye\n_____________________\nI'm not sure about the flying with CBD products.  Doing a little digging on the web, I found a statement from the TSA concerning medical cannabis (even if someone has a valid card from the state);  there was no specific mention if CBD was exempted from the policy:\n\n\n\"Thank you for your e-mail concerning the Transportation Security Administration's (TSA) policy for allowing passengers with State authorized cards to bring marijuana onboard commercial airlines.\nAlthough TSA has no regulations addressing possession and transportation of marijuana, possessing marijuana in any detectable amount is a crime under Federal law. Further, it is a crime under the laws of many States to possess or transport marijuana.\nIn the course of screening passengers and their belongings for prohibited items (weapons, explosives and other objects that may pose a risk to aviation security), Transportation Security Officers (TSOs) sometimes discover marijuana or other items that are illegal under State and Federal laws. When this occurs, TSA's standard operating procedures require TSOs to report evidence of potential crimes to law enforcement authorities. It is up to the responding law enforcement officer, not our TSOs, to evaluate the circumstances and decide whether to arrest a passenger or confiscate the illegal item.\nTSOs must contact a law enforcement officer when marijuana is discovered because (1) possessing marijuana is a crime under Federal law, and (2) TSOs cannot make an independent determination as to whether a passenger's documentation is sufficient to authorize possession of marijuana under State law. Law enforcement officers must be contacted even if a passenger is carrying a State-issued cannabis card or other documentation indicating that the marijuana is for medical purposes.\"\n\nThe whole thrust of the letter seems to indicate that , even w/ CBD products and even with a vaild medical recommendation, there is no protection.\n\n\nAs for the CBD in a standard urine test, I'll cut and paste the link of an excerpt between the folks at the website The Cannabist  and one director of science at Quest Diagnostics and also another noted scientist in cannabis circles,  in a nutshell, CBD isn't on most urine test (just THC & metabolites) but even minute amounts of THC found in many cannabis products might be found and there's some controversy if CBD converts to THC in any non-negligible amount:\n \nhttp://www.thecannabist.co/2017/03/10/marijuana-drug-test-cbd-cannabidiol-positive/74014/\n\nHope you like these fascinating reads!\n\ndrpark","image":null}},{"node":{"id":"Question_10757-markdown","title":"Charlotte's Web Good As Jayden's Juice?","slug":"charlottes-web-good-as-jaydens-juice","content":"\"Today the Doctor recommended to me to take something like Jayden's Juice for my Anxiety/Depression/Agorphobia. I have been on different CBD oil and stared on Charlotte's Web. I have a lot left and wonder if I wasn't taking enough? And what is the difference between the two?\n\"\n_____________________\nPlease see answer to your second question.\n\ndrfrye","image":null}},{"node":{"id":"Question_10752-markdown","title":"Hi, any tinctures product that you would recommend to treat severe insomnia? ","slug":"hi-any-tinctures-product-that-you-would-recommend-to-treat-severe-insomnia","content":"\"I have severe insomnia and I was wondering what products and what percentage of THC and/ or CBD would be best for me?\"\n_____________________\nI am not a doctor but I do use cannabis to treat my sleepless nights and have found it to be effective. That said, everyone is different to how they react to cannabis and this may or may not work for you. I have also found that it took me several products to find the one that works best for me, but that may not be the case for you.\n\nThere is some information that is important to think about before you embark on using cannabis for sleep issues:\n\n-First, is it anxiety that is keeping you up? If so, then you might want to avoid high THC strains or anything high in THC as this could exacerbate the issue. \n\n-Smoking or vaping may be a quick way to induce a sleepy feeling, especially with an indica strain but edibles are thought to keep you asleep longer. This is due to the way edibles are metabolized within your body.\n\n-There is not much recent research within this area but what I have found out there seems to indicate the combination of CBD and THC is most beneficial for sleeping. The right combination is dependent on your individual system.\n\n-You have the option to smoke/vape, tinctures, sub lingual sprays, and edibles. There are a lot of choices and I recommend going to a dispensary with a wide selection and knowledgeable bud tenders.\n\nSome top strains to smoke/vape (there are a lot of them):\n-Afghan Kush - Indica\n-GrandDaddy Purple - Indica with high levels of the terpene myrcene\n-CBD Critical Mass - Hybrid - higher in CBD than THC\n\nWith edibles, I always warn people to start with half the recommended dose (or even less) and try night by night. I have had sleepless edible nights from taking too much of an edible.\nTwo products I have heard a lot about but have not tried are Sensi Chew Insomnia and Auntie Dolores triple brownie bite or Auntie Dolores caramel corn. Remember edibles can take up to an hour to take effect so you can have sweet bite right after dinner and it will take awhile to take effect. Many people might recommend starting with a 5-10mg dose and working up from there. 10mg is usually enough for someone to feel somewhat altered, especially if you are new to cannabis, proceed with caution! \n\nMy favorite product for me is by Absolute Extracts and it is Sleepytime. It is a sub lingual spray and two sprays is just enough, if I do 3 or 4 it is too much. I have been given those popular indica gummies that dispensaries often readily recommend and I really was not a fan, even at smaller dosages. For some people they work well.\n\nHope this helps! \n \n\npamelahadfield","image":null}},{"node":{"id":"Question_10746-markdown","title":"Hello, I am a CDL license over-the-road truck driver. If I used the CBD patch on my back for pain relief, would I fail a drug screen test","slug":"hello-i-am-a-cdl-license-over-the-road-truck-driver-if-i-used-the-cbd-patch-on-my-back-for-pain-relief-would-i-fail-a-drug-screen-test","content":"\n_____________________\nUnfortunately, the cannabinoids CBD and THC present in the most popular transdermal patch do enter the blood stream and are associated with psychoactive effects. I recently researched the literature to find out if positive blood tests for cannabinoids have been documented in patients using transdermal body balms in the concentrations available in standard dispensary preparations. To date, there have been no reports of positive blood tests using transdermal body balms, lotions and massage oils. This may be a safer option for you. \n     If you hold a Class A license I caution you to be cautious with your use of medical cannabis. If you are in an accident in which injury, property damage, civil litigation or criminal action occurs you will be drug tested using industrial testing methods that are highly sensitive and specific. Additionally, you will place the physician who authorized you at professional risk.\n\ndrsumchai\n_____________________\nI agree with Dr. Sumchai, that topicals like salves and balms are not likely to cause a positive drug test.  While CBD is not psychoactive, most transdermal CBD patches will have tiny amounts of THC that are not enough to cause mental impairment (particularly in the company of CBD which mitigates the psychoactivity of THC), but are enough that you could test positive for THC.  Cannabis salves and creams generally have THC which does not pass through moist, intact, healthy skin, but might if the skin is very dry with micro-abrasions. If the latter occurs, then theoretically, it might be possible to test positive. Using a topical on healthy skin would be the safer route. \n\ndrfrye","image":null}},{"node":{"id":"Question_10735-markdown","title":"What is the best choice for a CBD supplement to counter seizures?","slug":"what-is-the-best-choice-for-a-cbd-supplement-to-counter-seizures","content":"\n_____________________\nIt is very important that you discuss with your neurologist the adverse effects that you are experiencing with Keppra, so that s/he can tailor your dose and/or switch you to a different medication, safely. \n\nAs a supplement, CBD may be helpful for the prevention of seizures. Since ideally you should be covered around-the-clock, longer acting formulations are desirable. These include oral tinctures, which last approximately 2-4 hours and edibles, which last approximately 6-8 hours. CBD oil may be added to your own foods or beverages and ingested, which will give you similar coverage as could be obtained from purchasing edibles containing CBD. \n\ndredmunds","image":null}},{"node":{"id":"Question_10730-markdown","title":"What is the difference between cannabinoids and terpenes?","slug":"what-is-the-difference-between-cannabinoids-and-terpenes","content":"\"I hear people talk about cannabinoids and I know a little bit about CBD and THC, mainly the difference between them. But what is the difference between terpenes and cannabinoids and why should I care? My bud tender has never mentioned terpenes to me when I buy flower from him.\"\n_____________________\nCannabinoids and terpenes are found in every strain of marijuana and it’s these synergistic elements that create the ‘entourage effect’. This means we know that when cannabinoids work in conjunction with terpenes that the sum of the whole is greater than the individual parts. Some argue that when you divorce one element from the rest, that the medicine becomes less effective. No doubt, cannabinoids seem to have a much higher profile in the dialogue surrounding cannabis. This is due to the fact that cannabinoids are more known to create a certain effect such as CBD is a known anti inflammatory or THC can often treat insomnia by helping you sleep.\n\nTerpenes however are connected to the overall aroma and the individual flavors you may taste when you smoke. It is due to this that terpenes are more often discussed when we are talking about flower, rather than say a sub lingual spray. Terpenes come from the oils on the cannabis plant and each one yields a different flavor which is why some my be minty and yet others taste like citrus. The synergy that happens between cannabinoids and terpenes relate back to the endocannabinoid system in our body. This is the system that is literally built to receive cannabinoids. So for instance when you inhale THC this binds to unique receptors in your brain stimulating a certain effect. Likewise, terpenes have their own effect. A well known terpene limonene is known to create a happier mood and decrease a feeling of depression (for some).\n\nThe bottom line is that both are important even though terpenes may be lesser known and not talked about as much. Cannabinoids and terpenes work hand in hand it seems. If you are really interested in knowing what terpenes are in your flower most lab test will reveal this.\n\nmark","image":null}},{"node":{"id":"Question_10699-markdown","title":"I have muscle pain and depression, what is the best CBD strain for me with the lowest THC?","slug":"i-have-muscle-pain-and-depression-what-is-the-best-cbd-strain-for-me-with-the-lowest-thc","content":"\n_____________________\nI'm aware of two strains that are extremely low in CBD; AC/DC and Charlotte's Web.  AC/DC is a sativa strain with a CBD:THC ratio of 20:1 while Charlotte's Web is a hybrid which has less than 0.3% THC!  These strains were developed to help treat pain, anxiety, epilepsy, multiple sclerosis, and chemotherapy side effects without intoxication. Charlotte's Web was created specifically for a young epileptic named Charlotte by Colorado growers and may be more difficult to find. \n\nRemember that THC can have uplifting effects, so you might consider something with more THC that is still relatively low on the psychoactive scale, such as the sativa Harlequin.  Harlequin has a 1:1 ratio of CBD:THC so may counteract depression while still maintaining cognition. \n\ndredmunds","image":null}},{"node":{"id":"Question_10695-markdown","title":"I would like advice on the use of CBD, CBN and THC for insomnia; what is best?","slug":"i-would-like-advice-on-the-use-of-cbd-cbn-and-thc-for-insomnia-what-is-best","content":"\n_____________________\nThere isn't a simple \"best\" answer, and patients react differently to different strains, but I'm happy to offer some general information. \n\nCBD is very effective at treating anxiety and can have a sedating, relaxing effect. If your insomnia is due to anxiety or racing thoughts, a higher ratio of CBD:THC may be helpful.  \n\nTHC can be energizing and uplifting for some patients and can worsen anxiety in others.  Strains lower in THC may be better for insomnia.  CBD also counteracts some of the effects of THC.\n\nCBN is sedating, and CBN levels increase as marijuana ages, so you might consider older cannabis!\n\nIn general, patients find that indica strains tend to work better for insomnia than sativa strains. \n\nAlso, while vaporizing is faster-acting, edible cannabis is longer-acting; so an edible indica might be the solution for maintaining sleep and comfort for a full 6-8 hour rest period.  \n\ndredmunds\n_____________________\nYou might try: Alta California's Botanicals: Insomnia Relief Tincture. It has a good percentage of CBN, which is good for sleep.\n\neden","image":null}},{"node":{"id":"Question_10690-markdown","title":"What is the best ratio and dosage of CBD and THC for my cancer?","slug":"what-is-the-best-ratio-and-dosage-of-cbd-and-thc-for-my-cancer","content":"\"I don't want to feel high, but I do want to feel better that I currently do.\"\n_____________________\nCan you tell me why the 12:1 CBD/THC ratio was not recommended for you? I have done some research that suggests that too high of a THC ratio can proliferate Estrogen Positive cancer. I've read a couple of websites that suggest a 3:1 CBD/THC ratio is better, however, there is not a lot of information about it. Has your girlfiend been feeling better with the 1:1 ratio at all?\n\nladyinleopard\n_____________________\nContrary to what these professionals are saying I have seen cannabis bring several people back from hell using Rick Simpson oil in conjunction with Amber oil to cure cancer including My own dad   & it's been 11 years. She must do more than use the oil. She must also consume a high alkaline diet(check out Dr Sebi) as well as making your own butter and tinctures with them(comes out way cheaper) They have this great new machine called magical butter machine. Get it use it often & God Bless FYI DR SEBI CURED CANCER WAY BACK IN THE 90's himself so if I was you I'd do some due diligence on the research tip. God Bless\n\nsirkofyork\n_____________________\nStage 2 prostate cancer, or cancer that has not grown outside the prostate capsule and have a higher PSA level then 10. As with stage I cancers, active surveillance is often a good option for men whose cancer is not causing any symptoms and who are elderly and/or have other serious health problems. Radical prostatectomy and radiation therapy (external beam or brachytherapy) may also be appropriate options.\n\nUsing THC or CBD oil and suppositories are unproven ways to treat prostate cancer. In other words there have never been human clinical trials using cannabis to treat prostate cancer. That being said, the other question would be is there any harm in using them? As far as I can tell the answer is no. The primary thing to remember is to be in contact and follow up with your urologist so that they can keep an eye on your condition and not to rely on any cannabis product to be the only modality to treat any type of cancer.\n\nPerry Solomon, MD\n_____________________\nI am sorry to hear that has occurred. There have been no studies on humans as to the effectiveness of cannabis to treat any type of cancer, including prostate cancer. There is anecdotal reports of patients who have used Rick Simpsons oil to help treat prostate cancer instead of having prostate surgery when the cancer is isolated to the prostate and not spread. I am sure that your urologist and oncologist have recommended treatment that they have found to be helpful when the cancer has spread to the bones. That being said, there is no downside to using cannabis if you are looking to some pain relief if the cancer is causing you bone pain. Using a 1:1 CBD/THC ratio may give you pain relief.\n\nPerry Solomon, MD\n_____________________\nIdeally, your wife should be in a research study because there is a lot happening right now regarding ovarian cancer. \nBoth THC and CBD appear to be toxic to cancer cells but obviously a lot more research needs to be done. The biggest problem with ovarian cancer is the development of resistance to the chemotherapy so lots of research is being done on immunotherapy but she can be on the cannabis oil or a tincture now.\nUnfortunately, no one can tell you exactly how the Cannabis should be taken for optimal outcome. To be functional it makes sense to do CBD during the day when things have to be done and THC can be added when she does not have to drive or do business. CBD is great for stopping pain and inflammatory symptoms and it will calm anxiety and THC can give a nice uplift with a happy mood. CBD: THC in a 8:1 nonalcoholic tincture oral spray can work well in place of nonsteroidal anti-inflammatory drugs and she will not be hi; 4:1 works well for inflammation and pain but it will be psychoactive; 2:1 is psychoactive but may really help her attitude relax yet allow her to get things done around the house like fixing a nice meal and being with the family.\nI think anyone can use our full website but I am asking the office for clarity since I'm not 100% certain, I'm just one of the doctors here and I may not be aware if there's a portion of the website that is unavailable for out-of-state clients.\n\ndrolson\n_____________________\nI'm very sorry to hear of your health challenges. Your situation must be approached from many directions for true success. A high percentage of breast cancer cases our link to a deficiency of vitamin D and if the vitamin D level is not corrected you're more likely to experience metastasis and if it's still not corrected you have a higher risk of dying from vitamin D deficiency but it will be listed as breast cancer because most doctors do not know how to treat vitamin D deficiency. For optimal health your blood level of vitamin D must be above 50 ng/mL and that usually requires the supplements of about 10,000 international units of vitamin D3 per day.\nDo high CBD low THC in a nonalcoholic tincture (my preference is medium chain triglyceride oil from coconut) 2 to 3 times per day for optimal support of your immune system, pain relief, anxiety and stress relief as well as protection for your cardiovascular and neurological systems. You will not feel psychoactive effects with high CBD cannabis but if you would like a psychoactive effect you can always add more THC.\nPlease read a book, \"Sex, Lies and Menopause\" by Wiley and Taguchi and consider a second opinion with Dr. Taguchi, who happens to have the longest live breast cancer patients because she re-balances their hormones with true bio identical's to their 20 year old level of hormones proving that peaking the true bio identical estradiol and bio identical progesterone actually stimulate P 53 the guardian of your genome to cause involution of your cancer cells. \nThis does not mean that you forgo western treatment because that actually will be necessary but the cannabis will help you greatly and as soon as you are finished with your treatments you should consider starting on the Wiley protocol to keep the cancer from ever returning.\nGood luck, you have a lot of reading ahead of you and lots of decisions to make but the high CBD cannabis will keep your brain sharp and focused helping you make your decisions.\nDon't hesitate to stop doctors if they try to put a lot of negative suggestions in your brain, You have the right to request that they stay on the positive side to help support you, and not break you down.\n\n\ndrolson\n_____________________\nBoth  CBD and THC have demonstrated anti-proliferative activity in animal studies, however, there are no clinical trials to establish the optimal ratios of THC:CBD in treating cancer in humans. Most of the available literature is based on anecdotal evidence and recommends using a ratio with the maximum amount of THC that is tolerated.  I would suggest starting with a THC:CBD ratio of 1:10 - 2.5mg THC: 25mg CBD and increasing that dose as tolerated. Realm of Caring recommends a CBD dose of 50mg twice daily. I have a patient with Hodgkin's lymphoma that has responded to this dose, which is very low when compared to the Rick Simpson protocol of 60 grams (60,000 mg).   With high THC doses, the most significant side effects are going be mental impairment and possibly low blood pressure and heart rate that may cause dizziness, light headedness, or fainting. Also, I'd like to mention that  European studies have shown that in animal models, CBDa, the acidic precursor to CBD has even higher anti-tumor and anti-inflammatory activity than CBD. \n\ndrfrye\n_____________________\nYou're right that this is a very complicated and controversial issue and unfortunately, there is no clear cut answer.  \n\nMost evidence supports CBD as being a key anti-tumor agent in marijuana and has been acknowledged as such by the National Cancer Institute.  The American Association of Cancer Research published a paper demonstrating that CBD inflicts programmed-cell death in breast cancer cells, regardless of Estrogen receptor positivity, while preserving normal breast cells.  \n\nTHC also has anti-tumor properties and inhibits cell cycle progression in breast cancer cells. It has been said that THC may increase estrogen levels and may promote breast cancer growth in ER+ tumors, but there is not strong evidence to support this statement. \n\nUnfortunately, much more research will need to be done before we can provide any clear guidance on what the \"correct\" ratio of CBD/THC might be (if there is one) for the treatment of specific types of cancer.  I would approach it from a tolerance standpoint and also one that provides symptomatic relief of pain and/or treatment side effects.  In general, this would mean a higher ratio of CBD/THC while at the same time minimizing psychoactive effects of THC.  \n\nIt is true that the rectal suppositories provide greater bioavailability (upwards of 70%)  than inhaled or ingested cannabis (approximately 20%).  \n\nRick Simpson's oil is a full-plant cannabis extract containing high amounts of THC, CBD, and other cannabinoids.  It differs from CBD-oil which is often extracted from hemp and contains (mostly) CBD. The theory behind Rick Simpson's oil is to provide the patient with maximum possible amounts of all cannabinoids, in a more nature balance that is found in the plant.  Another theory is that cannabinoids work synergistically, which would support the use of such a product.  \n\ndredmunds\n_____________________\nI recently tried to answer a similar question for the treatment of stage 4 breast cancer... Unfortunately, there is not a defined ratio of CBD/THC nor known dosing that is optimal for different types of cancer. Both CBD and THC have anti-tumor properties and may work synergistically. \n\nRick Simpson's oil has a high concentration of THC, CBD, and other cannabinoids and has been touted as being effective not only because of these high concentrations but because it is a \"whole-plant\" extract. \n\nBecause THC is the main psychoactive ingredient in marijuana, some patients don't tolerate high concentrations of THC well.  My general suggestion is to consider what is tolerable for any given patient on an individual basis and to focus on symptomatic relief of pain and/or side effects of treatment, including chemotherapy. Many patients have been able to tolerate chemotherapy much better while supplementing with cannabis.  \n\ndredmunds\n_____________________\nWe have been receiving a lot of questions similar to yours for a variety of different types of cancer, and appropriately so! You may want to refer to my answer to a couple questions recently on breast cancer and throat cancer, and Dr. Frye's answer to one regarding brain cancer. \n\nThe bottom line is, there is no \"best\" ratio known.  Clinical trials will need to be performed in humans to help us understand what ratios and/or dosages are most effective in different types of cancer.  We do know that in-vitro studies have demonstrated both CBD and THC to have anti-tumor properties, and there is anecdotal evidence that certain patients have had cancer go into remission following cannabis therapy. \n\nIn general, I recommend dosing according to what an individual patient can tolerate, which usually is a high CBD/THC ratio, because THC in high doses can have undesirable effects for many patients.  Also, many patients find that chemotherapy side effects are more tolerable when supplementing with cannabis.  If you are going to be working and/or driving while undergoing cannabis therapy, I would strongly encourage you to avoid THC during these times for obvious safety reasons.  \n\ndredmunds\n_____________________\nFECO or Full extract Cannabis Oil or Hash Oil, Hemp oil or Rick Simpson Oil has gained much attention as a potential treatment for many forms of cancer. Patients have shared their success stories in treating their cancer with this healing oil. Not only does FECO help patients deal with the side effects of conventional cancer treatment (nausea, poor appetite, vomiting, pain, depression, anxiety, insomnia, to name a few), it also shows promise in helping to eliminate cancerous cells, prevent metastasis of exsiting cancer, and in preventing angiogenesis (formation of new blood vessels that feed cancerous growth). With FECO dosing can be difficult, but from my experience it seems that more is better, and patients should try to ingest as much oil as possible, while remaining functional and comfortable. No potential for overdose exsists, but extreme psychoactive effects are often not desired. As much variability exsists in the quantities of THC and CBD, and in extraction techniques, it is best to start low and slow and gradually increase the dose as tolerance is built up. \nDosing should be three times a day, with the goal of about a gram a day, with the goal of ingesting at least 60 grams of oil in total. Each patient is different, and variability in the potency of the oil can be significant. As such, dosing should be optimized to each patient's situation and goals.\n\nandrewvanmd\n_____________________\nIn response to @scotter1 comments. While it is always thrilling to see that people have responded in some way to different treatments for cancer, breast or otherwise, it is very important to remember that cannabis has never been shown to \"cure\" cancer in humans. A \"cure\" by most definitions is cancer-free for 5 years. There have been many many anecdotal reports from people reporting this as well as labs, etc. The main point to remember that it is important consider using cannabis in any form, in conjunction with proven medical treatments when there are not reactions between the two.\n\nThe main difficulty in proving that cannabis works is the Schedule 1 label that cannabis has and the tremendous difficulty that surrounds having studies approved. And even when they are the results can be several years down the road. I applaud people who have the open mind to try cannabis to help treat their diseases but also do not want them to ignore, refuse or stop taking proven medical ones.\n\nPerry Solomon, MD\n_____________________\nI think CBD is better in higher ratio for cancer if all you are looking for is to kill cancer cells.  I think THC helps manage some of the side effects though.  check out projectcbd.org.    I really believe in the power of this plant's medicine. Also, reduce sugar and alkalize your body.  Best of luck with your health.\n\ngenabedon\n_____________________\nAt this point it is important to remember that part of what you are doing with cannabis is improving quality of life. The science is exciting but lacking in detail it can only be used to point you in the right direction. Your decisions will have to be based on something and your girlfriend's 'experience' of the medicine can be part of your guide. What makes her feel better?\n\nI recommend Uwe Blesching's book: Cannabis Health Index http://cannabishealthindex.com/\n\neden\n_____________________\nCBD or cannabidiol is a non-psychoactive compound found in certain strains of cannabis that has potent anti-inflammatory and anti-anxiety effects. Inflammation is the underlying cause of many diseases and conditions. Try tinctures with various ratios to see what works best for you. CBD has very different effects than THC, mainly because of the way it interacts with our endocannabinoid system. CBD works to increase the levels of our bodie's own cannabinoids (endo-cannabinoids), by preventing their breakdown.\n\nandrewvanmd\n_____________________\nI am not a doctor so I can not comment on CBD vs THC for cancer cells. I would recommend that you read the following articles on Project CBD. I often refer to \nProject CBD for articles on CBD and cancer:\nhttps://www.projectcbd.org/cancer\n\nThere are many scientific studies that indicate CBD can inhibit cancer cell growth, but these are most often within lab rats or petri dishes. There is a lot of anecdotal story telling around CBD/THC stopping cancer in its tracks or putting it into remission, but these are not based on any clinical trials or concrete evidence (I do not stand agree or disagree with people's experience). There are new studies underway and one in particular of interest is being done regarding cannabis in conjunction with traditional treatment methods on melanoma and can be viewed in this HelloMD news segment:\nhttps://www.hellomd.com/health-wellness/hellomd-live-episode-8\n\nI can speak from my own experience that for inflammation a high CBD ratio tincture works very well. I typically consume a 20:1 2x a day for inflammation and I take a low dose of THC every day 2x a day of 2.5 mg which will not have any noticeable psychoactive effect but it does decrease anxiety. \n\nTo answer your question more specifically, I would be consuming both CBD and THC as both have systematic effects that may help you. This is called the entourage effect, in that they work together to create homeostasis within the body. \n\nI hope this helps!\n\npamelahadfield\n_____________________\nSince we have been profoundly handicapped in this country by not being able to do clinical trials regarding the benefits of cannabis, I don't think anyone has a hard and fast rule around the best ratio of CBD to THC for brain cancer. We do know that CBD does stop some brain cancers and may protects the brain from further damage. The higher the concentration of CBD the more pervasive it is. Rick Simpson oil tends to be a 1:1 ratio but most of the stories of cancer cures are antidotal. I understand that clinical trials are being conducted in Israel so in the meantime consider using your cannabis to buy time in hopes that we will have a more definitive answer in the near future. Since activities are limited when using THC because you're not allowed to be high in public, I think it is wise to take high CBD during the day and you can do more THC at home. Remember to always follow high THC with high CBD if you want to go to sleep because that will make an Indica in your body.\n\ndrolson\n_____________________\nUnfortunately, there is no exact answer for this question. Many people will use Rick Simpson oil and overtime you will become adjusted to the high so you can function on a day-to-day basis. Chemical testing should have been performed on the oil if you buy it in California through a dispensary or delivery service. Both THC and CBD are toxic to cancer so I give patients the option of going on a super high CBD for daytime use along with RSO for afternoon and evening or CBD during the day and a Sativa in the afternoon returning to CBD at night. I think as long as you're taking high-dose is of cannabis it does facilitate your immune system in reversing your disease state but until we can actually do clinical trials, keep in mind we are handicapped and all we can truly offer are antidotal stories. I'm certain you want more assurance than just an antidotal story. Most research is being done in Israel at this time but a few clinical trials have been started in the United States, I just can't tell you if they involve your type of cancer.\nJeanne Achterberg taught us that imagery also works when you're fighting cancer. When you take a dose of cannabis, Image that each drop is filled with millions of little, microscopic dogs that love you and their whole purpose in life is to help you live by running through your body and eating any cancer cells or cancer garbage they find especially since this is what dogs are good at, eating garbage and loving you for the opportunity. Keep your determination strong and you should be able to overcome the cancer and even buying a couple of years me produce profound benefits for you because our knowledge is increasing exponentially. I had one patient that was able to successfully stop her ovarian cancer by doing a medically supervised fast for 40 days but I'm not advising that for you, I am encouraging you to find what is going to work for you and believing it 100% and then allow it time to work. If you do high CBD, you will not feel the medicine for almost 3 weeks, don't give up. You are in the battle that is worth fighting, I just wish we had more answers for you.\n\ndrolson\n_____________________\nI am so sorry for anyone who has pancreatic cancer since my Father and his only sister both had pancreatic cancer so I have watched it first hand but that was more than 30 years ago and we have come a ways since then especially with cannabis. We have been lacking credible research studies but one research study has been started in Australia by Chris O'Brein Lifehouse that will study the effects of cannabis on pancreatic cancers. \nSince all cancers involve inflammation, CBD or cannabidiol or THCa from juicing green cannabis buds may help to reduce inflammation there by giving relief from the pain and potential GI obstruction.  In addition, I highly recommend the topical cannabis salve that is slightly dominant in CBD. Rub the salve on your upper abdomen between the ribs and the area of the upper back that corresponds to the 'bra line on a woman' but applying the salve throughout the posterior thoracic spine to stop the pain is greatly beneficial and should be done frequently at first and as the pain is coming under control you may start to spread out the application of the salve. For me, the more I use the salve the more effective the salve is and the longer the pain blocking effect works. The salve will not go systemic on anyone who applies it for you and there will be people who want to help you out in any way they can so please, put them to work applying your salve. If there is some fear of potential contamination with the cannabis, you may supply some gloves.\nIf you are experiencing too much nausea to do the tincture orally, you could vaporize high CBD cannabis like AC/DC, 30 parts CBD to 9 parts THC, so you may be a little tipsy but you likely will be out of pain in about 10-15 minutes and the AC/DC will calm anxiety so consider a high CBD vaporizing pen for fast relief. Remember, CBDs must be vaporized at a lower temperature or the quality of the CBD will be lost so have someone help you with CBD vape pens if needed. \nGood luck, you need to buy time to stay around since there is so much work being done on finding the correct treatment for pancreatic cancer. Hold intention to live and use your mind to be positive to keep your immune system healthy and strong. You may want to do searches on the net for papers you can read on treatment of pancreatic cancer using integrated medicine as well as all the big tools of Western medical treatment because a lot of support is done with healthy nutrition, digestive enzymes and positive imagery and other treatments.\n\ndrolson\n_____________________\nMy husband has had good luck controlling the growth of his metastatic colon cancer that has spread to his liver with Cannabis oil. We used 3 different oils for maximum exposure to different terpenes.  I would have liked him to try suppositories also, but he is \"Rectal-phobic\".  The oil was taken by capsule. Three times daily.\n\njeroling\n_____________________\nI'm sorry to hear you have been diagnosed with breast cancer. There is no reason to smoke or drink. A whole-foods, plant-based diet has been shown to be beneficial for managing cancer symptoms such as pain, fatigue, and apoptosis (cancer cell death.) \n\nnixie\n_____________________\nThe best dosage or best CBD to THC ratio for cancer has many anecdotal answers.  If you are looking for a science-based answer regarding using cannabis in cancer please read Dr. Solomon's answers on this thread. We do know the \"high\" from THC is definitely modified in character and intensity by the presence of CBD, so finding the right CBD to THC ratio for you would be important. As Dr. Solomon notes, cannabis has a remarkably benign toxicity profile - although too much can be unpleasant there have never been any reports of poisoning or organ damage despite many years of widespread use of the plant. This makes it safe to experiment freely, but still offers no way to judge different recommendations, such as best CBD:THC ratio for cancer.  I am usually an \"entourage effect\" proponent, unwilling to exclude part of the plant when I don't fully understand what all the parts contribute, so I'm inclined toward more holisitic, \"whole plant\" preparations. Some varieties are bred to express mostly CBD, so you can still manipulate the CBD:THC ratio by including those. I also think of cannabis as an excellent mood moderator, better than many medications taken daily for this purpose, and in treating cancer I see an important role for this action both for patient comfort and to support the well established relationship between positive attitude and better survival in cancer.   \n\ndrelkind\n_____________________\n \nMy mother was diagnosed in May of 2013 with 4 Cancer.She was given 3  to 6 months to live,not because of spreading but because of the location  of the tumor, it is abutting the aorta. she is 53 and also has MS.I  succeeded in saving her life by getting Rick Simpson Oil from this guy  in California.You can contact him if interested in getting some Oil:\nEmail... tplug05 at gmail dot com .\nPhone.....+1(559)420-0769 .\n\n\nJones leton90\n_____________________\nMy mother was diagnosed in May of 2013 with 4 Cancer.She was given 3 to 6 months to live,not because of spreading but because of the location of the tumor, it is abutting the aorta. she is 53 and also has MS.\nI succeeded in saving her life by getting Rick Simpson Oil from this guy in California.You can contact him if interested in getting some Oil:\nEmail... tplug05 at gmail dot com .\nPhone.....+1(559)420-0769 .\n\n\nalison leton","image":null}},{"node":{"id":"Question_10685-markdown","title":"Are there any negative side effects from using marijuana long term?","slug":"are-there-any-negative-side-effects-from-using-marijuana-long-term","content":"\"I mainly use CBD on a daily basis to control inflammation in my body. If my pain is acute, I vape some cannabis oil that contains THC and find relief. Are there any negative side effects known from long term/sustained usage. \"\n_____________________\nGreat question.  Cannabidiol (CBD) is one of over 60 cannabinoid compounds found in the marijuana plant.  Along with THC, it is one of the most prevalent.  CBD has shown much pharmaceutical promise, including treatment of nausea / vomiting, psychosis, anxiety, depression, inflammatory disorders, seizure disorders, and neurodegenerative disorders. It has also been shown to possess anti-oxidant and anti-tumor properties. CBD increases wakefulness, which can be a benefit for daytime use but may adversely effect sleep.  \n\nIn general, there is not a lot of information regarding long term use of cannabis, but heavy exposure to THC over time has demonstrated adverse effects on memory and cognition. Interestingly, CBD seems to counteract these THC-induced effects. More research needs to be done to determine if any negative side effects are associated with longterm CBD use. Similarly, it will be interesting to see if longterm CBD use confers benefits, such as decreased cancer risk.\n\ndredmunds\n_____________________\nThere has been no consistent scientific answer to the question of whether there are negative side effects associated with using cannabis over a long period. As a practical matter, there has obviously been an enormous uncontrolled experiment over the past 50 years addressing that question, and no evidence of serious negative side effects has been noted as prevalent in the experimental population.  Although great effort has been put into demonstrating adverse effects of long term use of cannabis in support of prohibitionism, this has only resulted in many equivocal studies and quite a few where there the results are compromised by poor methodology.  The metabolism of cannabis in humans is fairly well understood and gives no reason to expect long term negative side effects from toxic byproducts.  No specific toxicity to any organ has been identified (unlike ibuprofen, for example).  The only negative side effects I'd be concerned about have to do with inhaling the smoke of burning plants, or the vapor of solvents in extracts.  And I'd say both of those concerns are linked to frequency and amount of exposure.  In terms of behavioral effects, the old refrain of cognitive impairment and lack of motivation as side effects of long term use of marijuana has been essentially debunked by recent meta-reviews in which the various reported studies of this issues are pulled together and analyzed as a whole.  http://www.beyondthc.com/marijuana-doesnt-make-you-stupid-after-all/   \n\ndrelkind","image":null}}]}},"pageContext":{"limit":12,"skip":756,"numPages":66,"currentPage":64,"id":5084,"name":"CBD","slug":"cbd","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}