{"componentChunkName":"component---common-build-questions-template-js","path":"/questions-and-answers/gastroproresis","result":{"data":{"question":{"title":"gastroproresis","slug":"gastroproresis","createdAt":"October 8, 2020","image":null,"tags":[],"childMarkdownRemark":{"excerpt":"\"any suggestions for gastroporesis\n\" Hi there!\nThe endocannabinoid system (ECS) is largely devoted to  maintaining…","html":"<p>\"any suggestions for gastroporesis\n\"</p>\n<hr>\n<p>Hi there!\nThe endocannabinoid system (ECS) is largely devoted to  maintaining homeostasis (the tendency of organisms to auto-regulate and  maintain their internal environment at equilibrium). Deficiency or  malfunction of the ECS has become a focus for researchers seeking  treatment options for several maladies—especially those that have few,  if any, effective pharmocotherapeutic interventions, such as celiac  disease, MS, fibromyalgia, IBD and IBS. In fact, the scientific  community has recently termed the ECS malfunction: Clinical  Endocannabanoid Decifiency, or CEDC. CBD works by balancing and  supporting the ECS through its subtle effects on cannaboinoid receptor-1  (CB1) and cannaboinoid receptor-2 (CB2) receptors, as well as other  receptors that modulate serotonin, GABA, dopamine, and more.</p>\n<p>The  enteric nervous system (ENS) is an extensive network of neurons  comprised of two neural plexuses: the myenteric plexus, involved in motility/peristalsis; and the submucosal plexus, involved in intestinal and gastric secretions. CBD works to restore homeostasis in the ENS via modulation of the myenteric plexus, and the submucosal plexus ... \"The small bowel has its particular contraction pattern (the MMC), which is under control  of the myenteric plexus.\"\n<a href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752592/\">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752592/</a></p>\n<p>drkim</p>\n<hr>\n<p>CBD's balancing of the myenteric plexus lessens inappropriate and  painful intestinal contractions, and coordinates peristalsis; while balancing of the submucosal  plexus reduces inappropriate gastric and intestinal secretions. CBD's effects the submucosal plexus and myenteric plexus  factor into CBD's ability to alleviate symptoms of GERD, IBS, IBD and very likely gastroparesis. </p>\n<p>Cannabis also helps alleviate most symptoms of gastropareris, including nausea and vomiting, heartburn, poor appetite and pain. </p>\n<p>drkim</p>\n<hr>\n<p>In a 2012 study conducted, of twenty-four patients with  treatment-resistant gastroparesis, six patients were prescribed  Dronabinol (synthetic THC); ten were prescribed marijuana of varying  ratios; and eight were prescribed Dronabinol followed by marijuana of varying  ratios. Statistically significant improvement  in abdominal pain score was seen in patients who received either  cannabinoid treatment. When analyzed individually, both marijuana and  Dronabinol showed statistically significant improvement in abdominal  pain scores as well.\" However, the cannabis of varying ratios of CBD and  THC provided superior pain relief in comparison of Dronabibol  (synthetic THC), with an abdominal pain score reduction of 51% vs 26%,  respectively. The significant superiority of cannabis over Dronabinol is  likely due to the CBD, and perhaps other cannabinoids and terpenes.\n<a href=\"https://www.eventscribe.com/2018/ACG/ajaxcalls/PosterInfo.asp?efp=RFNSWFFHSFY2NDI0&#x26;PosterID=162433&#x26;rnd=0.147068\">https://www.eventscribe.com/2018/ACG/ajaxcalls/PosterInfo.asp?efp=RFNSWFFHSFY2NDI0&#x26;PosterID=162433&#x26;rnd=0.147068</a></p>\n<p>I hope this helps!</p>\n<p>drkim</p>","timeToRead":2}},"defaultImage":{"childImageSharp":{"fluid":{"base64":"data:image/jpeg;base64,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","aspectRatio":1.5,"src":"/static/1e164eb4ee29aff63b63675577d389d3/a07a5/question-default-image.jpg","srcSet":"/static/1e164eb4ee29aff63b63675577d389d3/decd9/question-default-image.jpg 150w,\n/static/1e164eb4ee29aff63b63675577d389d3/15aed/question-default-image.jpg 300w,\n/static/1e164eb4ee29aff63b63675577d389d3/a07a5/question-default-image.jpg 600w,\n/static/1e164eb4ee29aff63b63675577d389d3/701ee/question-default-image.jpg 800w","srcWebp":"/static/1e164eb4ee29aff63b63675577d389d3/483a3/question-default-image.webp","srcSetWebp":"/static/1e164eb4ee29aff63b63675577d389d3/e8bcc/question-default-image.webp 150w,\n/static/1e164eb4ee29aff63b63675577d389d3/4fec1/question-default-image.webp 300w,\n/static/1e164eb4ee29aff63b63675577d389d3/483a3/question-default-image.webp 600w,\n/static/1e164eb4ee29aff63b63675577d389d3/2ad7f/question-default-image.webp 800w","sizes":"(max-width: 600px) 100vw, 600px"}}}},"pageContext":{"id":12324,"slug":"gastroproresis","country":"US"}},"staticQueryHashes":["3949754563","4179947113","4202924991"]}